Does the guys in 40 year old virgin ever lose his virginity?

Human sexuality is the capacity to have erotic experiences and responses. A person's sexual orientation may influence their sexual interest and attraction for another person. Sexuality can have biological, emotional/physical or spiritual aspects. The biological aspect of sexuality refers to the reproductive mechanism as well as the basic biological drive that exists in all species, which is hormonally controlled. The emotional or physical aspect of sexuality refers to the bond that exists between individuals, and is expressed through profound feelings or physical manifestations of emotions of love, trust, and caring. There is also a spiritual aspect of sexuality of an individual or as a connection with others. Sexuality impacts and is impacted by cultural, political, legal, and philosophical aspects of life. It can refer to issues of morality, ethics, theology, spirituality, or religion. Some cultures have been described as sexually repressive.

Interest in sexual activity typically increases when an individual reaches puberty. Some researchers assume that sexual behavior is determined by genetics, and others assert that it is molded by the environment. This is the nature versus nurture debate, in which one can define nature as those behavioral traits that are due to innate characteristics, such as instincts and drives. The concept of nurture can be defined as the environmental factors or external stimuli that influence behavior, emotions, and thinking. Biological and physical differences include the human sexual response cycle among men and women.

Human behavior refers to the range of behaviors exhibited by humans and which are influenced by culture, attitudes, emotions, values, ethics, authority, rapport, hypnosis, persuasion, coercion and/or genetics.

The behavior of people (and other organisms or even mechanisms) falls within a range with some behavior being common, some unusual, some acceptable, and some outside acceptable limits. In sociology, behavior in general is characterised as having no meaning, being not directed at other people, and thus is the most basic human action. Behavior in this general sense should not be mistaken with social behavior, which is a more advanced action, as social behavior is behavior specifically directed at other people. The acceptability of behavior depends heavily upon social norms and is regulated by various means of social control. Human behavior is studied by the specialised academic disciplines of psychiatry, psychology, social work, sociology, economics, and anthropology.

The Jewish tradition devotes considerable attention to sexuality. Sexuality is the subject of many narratives and laws in the Tanakh and rabbinic literature.

The 40-Year-Old Virgin is a 2005 American romantic comedy film co-written and directed by Judd Apatow. The film, about a middle-aged man's journey to finally have sex, was co-written by its lead star, Steve Carell, though the film itself features a great deal of improvised dialogue. The film was released theatrically in North America on August 19, 2005 and was released on region 1 DVD on December 13, 2005.

An independent film is a professional film production resulting in a feature film that is produced mostly or completely outside of the major film studio system. In addition to being produced and distributed by independent entertainment companies, independent films are also produced and/or distributed by subsidiaries of major film studios. Independent films are sometimes distinguishable by their content and style and the way in which the filmmakers' personal artistic vision is realized. Usually, but not always, independent films are made with considerably lower film budgets than major studio films. Generally, the marketing of independent films is characterized by limited release, but can also have major marketing campaigns and a wide release. Independent films are often screened at local, national, or international film festivals before distribution (theatrical and/or retail release). An independent film production can rival a mainstream film production if it has the necessary funding and distribution.

Love Celeb (ラブセレブ, Rabu Serebu?) is a shōjo manga series created by Mayu Shinjo. Sakuya Ookochi, the main character from Sensual Phrase, also makes an appearance in this manga, as does Hakuron from the later spin-off Haou Airen.

Her Minor Thing is a 2005 motion picture. The romantic comedy is directed by Charles Matthau, written by Jim Meyers and Debra Meyers, and stars Estella Warren, Christian Kane, and Michael Weatherly.

The script's working title was "Men Are Jerks".