Transition in cell type parallels treatment response, disease progression in breast cancer
Several studies have suggested that a transition from epithelial ... and they found evidence that the growth factor TGF-beta may mediate EMT in cancer. "This study provides us with a new biologic understanding of breast cancer invasion and metastasis ...
Origin of aggressive ovarian cancer discovered
Cornell University researchers have discovered a likely origin of epithelial ... in transitional zones in the human ovary and other organs, such as the stomach, rectum and uterine cervix. Cornell University. "Origin of aggressive ovarian cancer discovered."
Why Does Bladder Cancer Come Back at a High Rate?
A number of factors contribute to the high rate of bladder-tumor recurrence, the most important being what is known as the field effect, a term used to describe the relation of bladder cancer to ... bladder consist of transitional epithelial cells, a ...
Scientists identify protein that spurs spread of colon cancer
PLAC8, a protein that until now has been poorly understood, appears to play a key role in the spread - or metastasis - of colorectal or colon cancer ... During this epithelial-to-mesenchymal transition, the gut loses its sheet-like structure, allowing ...
Scientists discover origin of aggressive ovarian cancer
Cornell researchers have discovered a likely origin of epithelial ovarian cancer (ovarian ... from stem cells found in that niche, according to the study published March 6 in the journal Nature. This stemcell niche lies in a transitional area known as ...