Yes it is.
The Mississippi River is the chief river of the largest drainage system in North America. Flowing entirely in the United States (though its drainage basin reaches into Canada), it rises in northern Minnesota and meanders slowly southwards for 2,530 miles (4,070 km) to the Mississippi River Delta at the Gulf of Mexico. With its many tributaries, the Mississippi's watershed drains all or parts of 31 US states and 2 Canadian provinces between the Rocky and Appalachian Mountains. The Mississippi ranks as the fourth longest and tenth largest river in the world. The river either borders or cuts through the states of Minnesota, Wisconsin, Iowa, Illinois, Missouri, Kentucky, Tennessee, Arkansas, Mississippi, and Louisiana.
Native Americans long lived along the Mississippi and its tributaries. Most were hunter-gatherers or herders, but some, such as the Mound builders, formed prolific agricultural societies. The arrival of Europeans in the 1500s changed the native way of life as first explorers, then settlers, ventured into the basin in increasing numbers. The river served first as a barrier – forming borders for New Spain, New France, and the early United States – then as a vital transportation artery and communications link. In the 19th century, during the height of Manifest Destiny, the Mississippi and several western tributaries, most notably the Missouri, formed pathways for the western expansion of the United States. Mississippi
The Missouri River is the longest river in North America, longest tributary in the United States and a major waterway of the central United States. Rising in the Rocky Mountains of western Montana, the Missouri flows east and south for 2,341 miles (3,767 km) before entering the Mississippi River north of St. Louis, Missouri. The river takes drainage from a sparsely populated, semi-arid watershed of more than half a million square miles (1,300,000 km2), which includes parts of ten U.S. states and two Canadian provinces. When combined with the lower Mississippi River, it forms the world's fourth longest river system.
For over 12,000 years, people have depended on the Missouri and its tributaries as a source of sustenance and transportation. More than ten major groups of Native Americans populated the watershed, most leading a nomadic lifestyle and dependent on enormous buffalo herds that once roamed through the Great Plains. The first Europeans encountered the river in the late seventeenth century, and the region passed through Spanish and French hands before finally becoming part of the United States through the Louisiana Purchase. The Missouri was long believed to be part of the Northwest Passage – a water route from the Atlantic to the Pacific – but when Lewis and Clark became the first to travel the river's entire length, they confirmed the mythical pathway to be no more than a legend. Missouri