Question:

How long does the brown recluse anti venom stay in your system after getting treated?

Answer:

There is no antivenom available in the U.S. to counteract the poisonous venom of the brown recluse spider. Controversial therapies include steroids and the drug dapsone (Avlosulfon).

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InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2YYes 
Key:MQJKPEGWNLWLTK-UHFFFAOYSA-NYYes 

Dapsone (diamino-diphenyl sulfone) is an antibacterial most commonly used in combination with rifampicin and clofazimine as multidrug therapy (MDT) for the treatment of Mycobacterium leprae infections (leprosy). It is also second-line treatment for prophylaxis (prevention) against Pneumocystis pneumonia (PCP) caused by Pneumocystis jirovecii (formerly P. carinii) in HIV patients in whom CD4 counts are below 200/mm3.

The United States of America (USA), commonly referred to as the United States (US), America, or simply the States, is a federal republic consisting of 50 states, 16 territories, a federal district, and various overseas extraterritorial jurisdictions. The 48 contiguous states and the federal district of Washington, D.C., are in central North America between Canada and Mexico. The state of Alaska is the northwestern part of North America and the state of Hawaii is an archipelago in the mid-Pacific. The country also has five populated and nine unpopulated territories in the Pacific and the Caribbean. At 3.79 million square miles (9.83 million km2) in total and with around 316 million people, the United States is the fourth-largest country by total area and third largest by population. It is one of the world's most ethnically diverse and multicultural nations, the product of large-scale immigration from many countries. The geography and climate of the United States is also extremely diverse, and it is home to a wide variety of wildlife.

Paleo-indians migrated from Asia to what is now the US mainland around 15,000 years ago, with European colonization beginning in the 16th century. The United States emerged from 13 British colonies located along the Atlantic seaboard. Disputes between Great Britain and these colonies led to the American Revolution. On July 4, 1776, delegates from the 13 colonies unanimously issued the Declaration of Independence. The ensuing war ended in 1783 with the recognition of independence of the United States from the Kingdom of Great Britain, and was the first successful war of independence against a European colonial empire. The current Constitution was adopted on September 17, 1787. The first 10 amendments, collectively named the Bill of Rights, were ratified in 1791 and guarantee many fundamental civil rights and freedoms.

Protostome Sicariidae

Leprosy, also known as Hansen's disease (HD), is a chronic infection caused by the bacterium Mycobacterium leprae and Mycobacterium lepromatosis. Leprosy takes its name from the Latin word Lepra, while the term "Hansen's Disease" is named after the physician Gerhard Armauer Hansen. It is primarily a granulomatous disease of the peripheral nerves and mucosa of the upper respiratory tract; skin lesions are the primary external sign. Left untreated, leprosy can be progressive, causing permanent damage to the skin, nerves, limbs and eyes. Contrary to folklore, leprosy does not cause body parts to fall off, although they can become numb or diseased as a result of secondary infections; these occur as a result of the body's defenses being compromised by the primary disease. Secondary infections, in turn, can result in tissue loss causing fingers and toes to become shortened and deformed, as cartilage is absorbed into the body.

Treatment for multibacillary leprosy consists of rifampicin, dapsone, and clofazimine taken over 12 months. Single dose multidrug therapy (MDT) for single lesion leprosy consists of rifampicin, ofloxacin, and minocycline. The move toward single-dose treatment strategies has reduced the rates of disease in some regions. World Leprosy Day was created to draw awareness to those affected by leprosy.

Antibiotics

InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2YYes 
Key:MQJKPEGWNLWLTK-UHFFFAOYSA-NYYes 

Dapsone (diamino-diphenyl sulfone) is an antibacterial most commonly used in combination with rifampicin and clofazimine as multidrug therapy (MDT) for the treatment of Mycobacterium leprae infections (leprosy). It is also second-line treatment for prophylaxis (prevention) against Pneumocystis pneumonia (PCP) caused by Pneumocystis jirovecii (formerly P. carinii) in HIV patients in whom CD4 counts are below 200/mm3.

The brown recluse spider or violin spider, Loxosceles reclusa, Sicariidae (formerly placed in a family "Loxoscelidae") is a spider with a venomous bite.

Brown recluse spiders are usually between 6–20 mm (1⁄4 in and 3⁄4 in), but may grow larger. While typically light to medium brown, they range in color from cream-colored to dark brown or blackish gray. The cephalothorax and abdomen may not necessarily be the same colour. These spiders usually have markings on the dorsal side of their cephalothorax, with a black line coming from it that looks like a violin with the neck of the violin pointing to the rear of the spider, resulting in the nicknames fiddleback spider, brown fiddler, or violin spider.

Antivenom (or antivenin or antivenene) is a biological product used in the treatment of venomous bites or stings. Antivenom is created by milking venom from the desired snake, spider or insect. The venom is then diluted and injected into a horse, sheep or goat. The subject animal will undergo an immune response to the venom, producing antibodies against the venom's active molecule which can then be harvested from the animal's blood and used to treat envenomation. Internationally, antivenoms must conform to the standards of pharmacopoeia and the World Health Organization (WHO).

The name "antivenin" comes from the French word venin, meaning venom, which in turn was derived from Latin venenum, meaning poison.

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The recluse spiders or brown spiders (genus Loxosceles), also known as fiddle-back, violin spiders or reapers, are a genus of venomous spiders known for their bite, which sometimes produces a characteristic set of symptoms known as loxoscelism. Recluse spiders are now identified as members of the family Sicariidae, having formerly been placed in their own family, the Loxoscelidae.

Venom Medicine

A spider bite is an injury resulting from the bites of spiders or other closely related arachnids.

Spiders are active hunters and rely heavily on their bites to paralyze and kill their prey before consuming it. They also bite in self-defense. While many spiders will never attack animals larger than themselves, some—e.g., Atrax robustus—exhibit a rather aggressive behavior and will stand their ground when approached by larger animals. Most spider bites occur when humans unintentionally press up against spiders and receive a defensive bite. On rare occasions, spiders may make prey mistakes and bite a human finger or other body part as though it were a caterpillar or other such insect.

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