Internal Ribosome Entry Site Regulates Translation of Kaposi's Sarcoma-Associated Herpesvirus FLICE Inhibitory Protein
Using both in vitro translation and cell transfection assays, we have identified an internal ribosome entry site (IRES ... coding sequences are present within a single transcript, in situ reverse transcriptase PCR results do not define how, or indeed ...
Active site plasticity revealed from the structure of the enterobacterial N-ribohydrolase RihA bound to a competitive inhibitor
The molecular surface of the active site does not show a tight complementarity to the ... that can be stabilized via substantially different interactions within the active site. Structural models obtained using natural occurring substrates support this ...
New Images Capture Cell's Ribosomes At Work
When the cell needs to produce more proteins, the DNA unzips into two separate strands, exposing the protein code so it can be duplicated by single-stranded messenger RNA (mRNA). The mRNA dutifully delivers that code to the ribosome, which somehow reads ...
Why Evolution is True
This is a clear, easy-to-understand work that shows you — with no compromising and no ... He goes through many, many arguments about this: how we do see adaptation to changing environments, how the DNA records support the change in the genome of life ...
A Nobel for Ribosome Structure
have won for X-ray crystallographic studies of the ribosome. Ribosomes are indeed significant ... the fundamental working units of a day-to-day living cell. The ribosome has a lot of work to do, and it does it spectacularly quickly and well.