The Geography of Indiana refers to the U.S. State of Indiana. Indiana is in the north-central U.S. and borders on Lake Michigan. Surrounding states are Michigan to the north, Illinois to the west, Kentucky to the south, and Ohio to the east. The entire southern boundary is the Ohio River.
The National Road (Cumberland Road) was the first major improved highway in the United States to be built by the federal government. The approximately 620-mile (1,000 km) long National Road provided a connection between the Potomac and Ohio Rivers and a gateway to the West for thousands of settlers. When rebuilt in the 1830s, the Cumberland Road became the first road in the U.S. to use the new macadam road surfacing.
The United States is a country in the Northern Hemisphere, Western Hemisphere, and the Eastern Hemisphere. It consists of forty-eight contiguous states in North America, Alaska, a peninsula which forms the northwestern most part of North America, and Hawaii, an archipelago in the Pacific Ocean. There are several United States territories in the Pacific and Caribbean. The term "United States", when used in the geographical sense, means the continental United States, Alaska, Hawaii, Puerto Rico, Guam, and the Virgin Islands of the United States. The country shares land borders with Canada and Mexico and maritime (water) borders with Russia, Cuba, and the Bahamas in addition to Canada and Mexico.
Science of drugs including their origin, composition, pharmacokinetics,
pharmacodynamics, therapeutic use, and toxicology.
Pharmacology (from Greek φάρμακον, pharmakon, "poison" in classic Greek; "drug" in modern Greek; and -λογία, -logia "study of", "knowledge of") is the branch of medicine and biology concerned with the study of drug action, where a drug can be broadly defined as any man-made, natural, or endogenous (within the body) molecule which exerts a biochemical and/or physiological effect on the cell, tissue, organ, or organism. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals.