The Geography of Oklahoma encompasses terrain and ecosystems ranging from arid plains to subtropical forests and mountains. Oklahoma contains 10 distinct ecological regions, more per square mile than in any other state by a wide margin. One of six states on the Frontier Strip, it is situated in the Great Plains and U.S. Interior Highlands region near the geographical center of the 48 contiguous states. Usually considered part of the South Central United States, Oklahoma is bounded on the east by Arkansas and Missouri, on the north by Kansas, on the northwest by Colorado, on the far west by New Mexico, and on the south and near-west by Texas.
The state has four primary mountain ranges: the Arbuckle Mountains, the Wichita Mountains, the Ozark Mountains and the Ouachita Mountains. Part of the U.S. Interior Highlands region, the Ozarks and Ouachitas form the only major highland region between the Rocky Mountains and the Appalachians.
Synthetic cannabis is a psychoactive designer drug created by spraying natural herbs with synthetic chemicals that, when consumed, allegedly mimic the effects of cannabis. It is often known by the brand names K2 and Spice, both of which are genericized trademarks used for any synthetic cannabis product. Synthetic cannabis is often termed spice product. There is controversy about calling Spice and K2 synthetic cannabis. "Synthetic" is considered a misnomer, because the ingredients contained in these products are mimics, not copies of THC.
Research on the safety of synthetic cannabis is now becoming available. Initial studies are focused on the role of synthetic cannabis in psychosis. Synthetic cannabis may precipitate psychosis and in some cases it may be prolonged. Some studies suggest that synthetic cannabinoid intoxication is associated with acute psychosis, worsening of previously stable psychotic disorders, and it may trigger a chronic (long-term) psychotic disorder among vulnerable individuals such as those with a family history of mental illness.
Tulsa // is the second-largest city in the U.S. state of Oklahoma and 46th-largest city in the United States. With a population of 393,987 (2012 US Census estimate), it is the principal municipality of the Tulsa Metropolitan Area, a region with 951,880 residents in the MSA and 1,122,259 in the CSA. The city serves as the county seat of Tulsa County, the most densely populated county in Oklahoma, and extends into Osage, Rogers, and Wagoner counties.
Tulsa was first settled between 1828 and 1836 by the Lochapoka Band of Creek Native American tribe. For most of the 20th century, the city held the nickname "Oil Capital of the World" and played a major role as one of the most important hubs for the American oil industry. Tulsa, along with several other cities, claims to be the birthplace of U.S. Route 66 and is also known for its Western Swing music.